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Determination of Prothrombin Time, Activated Partial Thromboplastin Time, Fibrinogen Level and Platelet Count in Patients with Type II Diabetes Mellitus

المصدر: مجلة الدراسات العليا
الناشر: جامعة النيلين - كلية الدراسات العليا
المؤلف الرئيسي: Elgeid, Mohammed Ali Awed (Author)
مؤلفين آخرين: Alhassan, Nazik awad (Co-Author) , Merghani, Leena Babiker (Co-Author) , Gaufri, Nasr Eldeen Ali Mohammed (Co-Author)
المجلد/العدد: مج13, ع52
محكمة: نعم
الدولة: السودان
التاريخ الميلادي: 2019
الشهر: مارس
الصفحات: 39 - 45
DOI: 10.33914/1382-013-052-021
ISSN: 1858-6228
رقم MD: 1006906
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, HumanIndex, IslamicInfo, EcoLink
مواضيع:
كلمات المؤلف المفتاحية:
Prothrombin Time
رابط المحتوى:
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المستخلص: Background: The majority of patients with type II diabetes mellitus develop atherothrombosis and venous thromboembolism (VTE).One of the most complications of diabetes mellitus that includes coagulation imbalance. This study aimed to measure prothrombin time, activated partial thromboplastin time, fibrinogen levels and platelet count in patients with type II diabetes mellitus. Materials and Methods: This is a case control study, 120 participants were enrolled; 60 patients were known cases with type II Diabetes Mellitus; their mean age is 49 years admitted to the Kosti Teaching Hospital, and the other 60 normal individual were selected as controls. Coagulation profile included; prothrombin time (PT), Activated Partial Thromboplastin Time (APTT) and Fibrinogen Level were measured by fully automated Coagulometer Analyzer Thrombolyser XRC, while the Platelets count was counted by full automated hematological Analyzer (Sysmex KXN-21).Data were analyzed by using statistical package for social sciences (SPSS) version 20.The differences were considered statistically significant when P value less than 0.05 Results: The glucose as expected and fibrinogen levels were statistically significantly higher in patients with type II Diabetes Mellitus in comparison with the normal control group with (P value (0.00 and 0.00) respectively. While PT and APTT were statistically significantly shorter in patients with type II Diabetes Mellitus in comparison with the normal control group with P value (0.00 and 0,00) respectively. Platelet count showed no statistically significance difference in patients with type II Diabetes Mellitus in comparison with the normal control group with P value (0.485). Conclusion: This study concluded that PT and APTT were significantly shorter, while the Plasma fibrinogen level was elevated in Sudanese diabetes mellitus patients

ISSN: 1858-6228

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