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Effect of Antimicrobial Peptides and Chemicals Produced by Animals on Liver Microsomal Enzymes CYP450

المصدر: مجلة سوهاج لشباب الباحثين
الناشر: جامعة سوهاج - كلية التربية
المؤلف الرئيسي: El-Sayed, Al-Baraa Akram (Author)
مؤلفين آخرين: McCann, Glen (Co-Author)
المجلد/العدد: ع1
محكمة: نعم
الدولة: مصر
التاريخ الميلادي: 2021
الصفحات: 166 - 176
ISSN: 2735-5535
رقم MD: 1123825
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch
مواضيع:
الأمراض | إنزيمات الكبد | مضادات الميكروبات | إفرازات الحيوانات | سموم الحشرات | المواد الكيميائية | الببتيدات
كلمات المؤلف المفتاحية:
Antimicrobial | Antimicrobial Peptides | CYP450
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المستخلص: The problem of multidrug-resistant pathogens as bacteria, fungi and yeast in addition to the restriction of using antibiotics as growth promoting substances in feed have attracted the attention for looking for alternative sources instead of conventional antibiotics like natural products which have antimicrobial activity. Much interests and researches have been focused on using natural antimicrobial peptides and chemicals extracted from animal secretions and some insect’s venoms as they exhibit antimicrobial activity against pathogens with lower resistance and higher synergistic effects if they were given in combination with blends of them. In this paper, some antibacterial peptides extracted from honeybees venom and expression with yeast Saccharomyces cerevisiae will be discussed as well as antimicrobial chemicals extracted from giraffes in addition to their inhibitory effects on liver microsomal enzymes CYP450 will be discussed also with its activity against microorganisms which are Agrobacterium rhizogenes, Aspergillus Niger, Candida albicans and E.coli using optical density analysis technique then their minimum inhibitory concentrations (MIC) will be determined as well as ICs 50 to measure the potency to inhibit a biological function using programmes like Gene5, graph pad prism and clone manager as well as testing antimicrobial activity of some chemicals which are provided in animal secretions.
ISSN: 2735-5535

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