Synthesis, Characterization and the Antimicrobial Activity of 3-"2-Phenylhydrazinyl"-2-Benzofuran1"3H"-One
| المصدر: | المجلة الجامعة |
|---|---|
| الناشر: | جامعة الزاوية - مركز البحوث والدراسات العليا |
| المؤلف الرئيسي: | Betrow, Abdul hakem. R. (Author) |
| مؤلفين آخرين: | Zriegh, Mohammed M. (Co-Author) , Elakesh, Esmail. O. (Co-Author) |
| المجلد/العدد: | مج19, ع1 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2017
|
| الشهر: | مارس |
| الصفحات: | 117 - 128 |
| رقم MD: | 1263071 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | EduSearch, EcoLink, IslamicInfo, AraBase, HumanIndex |
| مواضيع: | |
| رابط المحتوى: |
الناشر لهذه المادة لم يسمح بإتاحتها. |
| المستخلص: |
High yield efficiency and minimum steps are important strategies in synthetic organic chemistry. In this study, 3-(2-phenylhydrazinyl)-2-benzofuran-1(3H)-one was synthesized in one step, with high yield, through the condensation of two components. 2-carboxybezaldehyde (A) and phenylhydrazine (B) in methanol. The chemical structur was confirmed using a molecular spectroscopy tools (1H,13C-NMR, IR). The in vitro antibacterial and antifungal activities of this product was screened against two fungal strains (Candida albicans and Thielaviopsis paradoxa) and against three bacterial strains (Staphylococcus aureus, Escherichia coli and Bacillus subtilis). Results showed that the compound has antifungal and antibacterial activity. |
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