المستخلص: |
Background: In Sudan malaria is most commonly caused by infection with plasmodium falciparum, although by p.vivax. Malaria causes the most dangerous and highest rates of complication and mortality. Most malaria cases in 2018 reported by world health organization (WHO) in African region (213 million cases of malaria or 93% from all malaria cases in world and 70% being 5 years or younger). Objectives: The aim of this study was to measure and compare the mean of absolute lymphocyte count in malaria patients and control group, and to determine positive and negative predictive values of lymphocytopenia in malaria patients. Methods: It was conducted on 100 subjects with malaria as cases and 100 subjects without malaria as controls, at EL Genina Hospital after obtaining the ethical approval and the subjects' consent. It was done by testing the CBC, differential counts and absolute lymphocyte count then determining the means and p-values. The positive and negative predictive values were also determined. Results: It was found that the mean of TWBC count in case group was (7,13109/l), and (7,84109/l) in the control group, p value was (0.150). The mean of lymphocytes differential in case group was (20.73%) and (33.96%)in the control group, p-value was (0.000). While the mean of the absolute lymphocytes count in case group was (1.39109/l), it was (2.56109/l) in the control group, with a p value (0.000). This p-value indicated that there was significant lymphocytopenia in malaria patients. The positive predictive value was 83% and negative predictive value was 69%. Conclusion: This study concluded that there was nosignificantlymphocytopenia in malaria patients, and that lymp hoc ytopenia cannot be used as the key haema to logical indicator of malaria infection."
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