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الرئيسية > Study of the Effect of Fenugre...>مارك

Study of the Effect of Fenugreek Seeds on the Folliculogenesis in Super-Ovulated Female Rats

المصدر: المجلة الجامعة
الناشر: جامعة الزاوية - مركز البحوث والدراسات العليا
المؤلف الرئيسي: Elfituri, Zinab Y. K. (Author)
مؤلفين آخرين: Omran, Entesar A. A. (Author)
المجلد/العدد: مج23, ع2
محكمة: نعم
الدولة: ليبيا
التاريخ الميلادي: 2021
الشهر: يونيو
الصفحات: 137 - 162
رقم MD: 1264267
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, EcoLink, IslamicInfo, AraBase, HumanIndex
مواضيع:
الطب الحيوي | النباتات الطبية | التكنولوجيا الصيدلانية
كلمات المؤلف المفتاحية:
Ovulation Induction | Superovulation | Rhfsh | Diestrus Phase | Estrous Cycle | Atretic Follicles | Antral Follicles | Aqueous Extract | Fenugreek Seeds
رابط المحتوى:

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LEADER 03269nam a22002777a 4500
001 2017013
041 |a eng 
044 |b ليبيا 
100 |9 674007  |a Elfituri, Zinab Y. K.   |e Author 
245 |a Study of the Effect of Fenugreek Seeds on the Folliculogenesis in Super-Ovulated Female Rats 
260 |b جامعة الزاوية - مركز البحوث والدراسات العليا  |c 2021  |g يونيو 
300 |a 137 - 162 
336 |a بحوث ومقالات  |b Article 
520 |b The increase of the incidence of usage of ovulation induction and assisted reproductive technology (AST) for treatment of the anovulation disorders, causes increase of multiple pregnancy and ovarian hyper-stimulation syndrome as two main complications. These two complications are caused by hyper-stimulation of ovaries. Trigonella foenum-graecum (fenugreek) is an herbal plant that has been studied for fenugreek seed aqueous extract (FAE) on the folliculogenesis in super-ovulated female rats by quantifying the ovarian follicles; antral (mature follicle) and atretic follicles. Twenty-four 7-8 week-age cyclic Sprague Dawley female rats were divided into three groups (A, B and C). Group A considered as control group, the female rats in group B and C treated with fenugreek seed aqueous extract 500mg/kg and 1000mg/kg respectively. The extract was administering orally into rats in treated groups for 14 days. Vaginl smears were taken and examined daily to determine the different phases of estrous cycle. During diestrus phase of estrous cycle, the female rats in the three groups were treated with subcutaneous injection of decreasing doses of recombinant human FSH (rhFSH) to induce the superovulation. In next day (proestrus phase), the rats were sacrefied and both ovaries of each rat were removed for histological examination. Administering of 500 and 1000mg/kg body weight of the extract caused significant reduction in the number of antral follicles (p-value < 0.005), while the number of atretic follicles was increased significantly (p-value < 0.005) in both treated groups compared to control group. Moreover, the atretic follicles’ number was significantly (p-value = 0.01) higher in group C (treated with 1000mg/kg of FAE) compared to group B (treated with 500mg/kg of FAE). As an outcome of this study, FAE showed an effect on the fluculogenesis by reducing the number antral follicles and increasing the atretic follicles’ number. 
653 |a الطب الحيوي  |a النباتات الطبية  |a التكنولوجيا الصيدلانية 
692 |b Ovulation Induction  |b Superovulation  |b Rhfsh  |b Diestrus Phase  |b Estrous Cycle  |b Atretic Follicles  |b Antral Follicles  |b Aqueous Extract  |b Fenugreek Seeds 
700 |9 674008  |a Omran, Entesar A. A.  |e Author 
773 |4 العلوم الإنسانية ، متعددة التخصصات  |4 العلوم الاجتماعية ، متعددة التخصصات  |6 Humanities, Multidisciplinary  |6 Social Sciences, Interdisciplinary  |c 010  |e University Bulletin  |l 002  |m مج23, ع2  |o 0928  |s المجلة الجامعة  |v 023 
856 |u 0928-023-002-010.pdf 
930 |d n  |p y  |q n 
995 |a EduSearch 
995 |a EcoLink 
995 |a IslamicInfo 
995 |a AraBase 
995 |a HumanIndex 
999 |c 1264267  |d 1264267 

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