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The Radiochemical Purity of Free Tc99m Pertechnetate and Tc99m Radiopharmaceuticals during in-Use Shelf-Life

المصدر: مجلة الدراسات العليا
الناشر: جامعة النيلين - كلية الدراسات العليا
المؤلف الرئيسي: .Abdallah, Alsiddig K. A (Author)
مؤلفين آخرين: Gamil, Abdrhman M (Co-Author) , .Fadulallah, Salah A (Co-Author)
المجلد/العدد: مج15, ع6
محكمة: نعم
الدولة: السودان
التاريخ الميلادي: 2020
الصفحات: 59 - 68
DOI: 10.33914/1382-015-006-009
ISSN: 1858-6228
رقم MD: 1298400
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, EcoLink, IslamicInfo, HumanIndex
مواضيع:
كلمات المؤلف المفتاحية:
Radiochemical Purity | Tc99m Pertechnetate | Tc99m Radiopharmaceuticals | Radiopharmaceuticals Compounding
رابط المحتوى:
صورة الغلاف QR قانون

عدد مرات التحميل

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LEADER 02726nam a22002897a 4500
001 2056697
024 |3 10.33914/1382-015-006-009 
041 |a eng 
044 |b السودان 
100 |9 689242  |a .Abdallah, Alsiddig K. A  |e Author 
245 |a The Radiochemical Purity of Free Tc99m Pertechnetate and Tc99m Radiopharmaceuticals during in-Use Shelf-Life 
260 |b جامعة النيلين - كلية الدراسات العليا  |c 2020 
300 |a 59 - 68 
336 |a بحوث ومقالات  |b Article 
520 |b Radiochemical purity determines the biodistribution of free Tc99m pertechnetate and Tc99m radiopharmaceuticals. The radiochemical impurities in free Tc99m pertechnetate is the hydrolyzed Tc99m, while the radiochemical impurities in Tc99m labeled radiopharmaceuticals are free Tc99m pertechnetate and hydrolyzed Tc99m. The impact of these impurities includes poor image quality which leads to wrong diagnosis and also gives unnecessary radiation dose to the patient. The objective of this study was to find out the influence of storage temperature on radiochemical purity of Tc99m pertechnetate and Tc99m radiopharmaceuticals. 65 Samples of free Tc99m pertechnetate and Tc99m radiopharmaceuticals were utilized for radiochemical purity determination at storage temperature from 25 C0- 29 C0 by the chromatography method which is consist from mobile phase and ITLC strips as stationary phase. The mean radiochemical purity resulted was 98.2% with STD 0.7 for all samples. Radiochemical purity of free Tc99m pertechnetate and Tc99m radiopharmaceuticals remains stable in 95.4% of the samples and 4.6% of the samples were out of the internationally acceptable limit. This may be attributed neither to temperature nor to the designed storage period. It is recommended that, follow up of quality assurance protocol including double check should be implemented. 
653 |a الأدوية المشعة  |a الشوائب الكيميائية  |a المواد الإشعاعية 
692 |b Radiochemical Purity  |b Tc99m Pertechnetate  |b Tc99m Radiopharmaceuticals  |b Radiopharmaceuticals Compounding 
700 |9 689244  |a Gamil, Abdrhman M  |e Co-Author 
700 |9 689246  |a .Fadulallah, Salah A  |e Co-Author 
773 |4 العلوم الإنسانية ، متعددة التخصصات  |4 العلوم الاجتماعية ، متعددة التخصصات  |6 Humanities, Multidisciplinary  |6 Social Sciences, Interdisciplinary  |c 009  |l 006  |m مج15, ع6  |o 1382  |s مجلة الدراسات العليا  |t Journal of Graduate Studies  |v 015  |x 1858-6228 
856 |u 1382-015-006-009.pdf 
930 |d y  |p y  |q n 
995 |a EduSearch 
995 |a EcoLink 
995 |a IslamicInfo 
995 |a HumanIndex 
999 |c 1298400  |d 1298400