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الرئيسية > Hematological and Biochemical...>الوصف

Hematological and Biochemical Parameters Changes Associated with Coronavirus Disease "COVID-19" for some Patients in Missan Province

المصدر: مجلة ميسان للدراسات الأكاديمية
الناشر: جامعة ميسان - كلية التربية الأساسية
المؤلف الرئيسي: Abuali, Anas S. (Author)
المجلد/العدد: مج23, ع49
محكمة: نعم
الدولة: العراق
التاريخ الميلادي: 2024
الشهر: آذار
الصفحات: 68 - 80
DOI: 10.54633/2333-023-049-007
ISSN: 1994-697X
رقم MD: 1458007
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, HumanIndex
مواضيع:
مؤشرات الدم | الكيمياء الحيوية | فصائل الدم | العراق
كلمات المؤلف المفتاحية:
COVID-19 " SARS-Cov-2" | Hematological | Biochemical Parameters | Blood Grouping | Missan Province
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المستخلص: Aim of study: COVID-19 an infectious respiratory illness caused by the severe acute respiratory syndrome–corona virus 2 (SARS-CoV2), has now spread to multiple countries including Iraq, therefore this study aimed at the detection of the relationship of hematological and biochemical markers with SARS-CoV-2 infection in Missan city. Method: The study was performed in Period between (First of November -2021 to First of May- 2022), the data and blood samples were collected from 92 (55 males and 37 females) in Maternity and Baby hospital (COVID-19 center ).the patients were conformed as positive for SARS-CoV-2 nucleic acid by fluoresce RT-PCR .Each infected patient was subjected to the blood grouping test according to the procedure that described in kit of blood grouping from supplier in Chennai(India). Five (5 ml) of venous blood samples were collected, Each blood sample separated into two tubes, The first sample (2 ml) of the blood added to EDTA tube for hematological assessment, the second blood sample (3 ml) added to the tube without anticoagulant and centrifugation for (10 minutes) at 3000 rpm, the serum was stored in (-20C˚) freezer till handled for biochemical analysis and all biochemical parameters were performed in laboratory of Baby and Maternity hospital according to the standard methods that described in the analysis kits products in Spinach Company Spain react. Complete blood picture (CBC) were shown from the collected blood samples by automatic methods (System X kx-21n automated hematology analyzer; JAPAIN CARE CO., LTD).

The results: The obtained results from this study observed the males were more infected with COVID -19 in percentage (59.7%), while the females were reported (40.2%) of all cases, high incidence of Covid-19 was reported in the ages between (51-60) years in percentage (31.5%) cases, followed by the ages between the years (61 -70 or more ), the infection with Covid-19 found in blood group (A) in percentage (58.6%), followed by blood group (O) in percentage (28.2%), the most common symptoms were fever in percentage (66.3%), cough (45.6%). Hematological analysis the blood samples significant decrease in red blood cells (RBCs), white blood cells (WBCs) and lymphocytes as compared normal value in (p < 0.05), while the haematocrit (HCT), hemoglobin (Hb), Platelets (Plt) and neutrophiles observed significant increase as compared with normal values. The biochemical analysis observed significant increase in Alkaline phosphatase (76.08%), creatinine (47.82%), blood urea (66.31%) as compared with normal values. significant increase in AST and ALT) in percentage (63.04%, 52.17%) respectively, blood glucose increased in patients (57. 61%) as compared with normal values, significant increase in the level of blood as compared with normal values .Significant increased LDH (63.04%), Firritin (78.26%), C-Reactive protein (84.78%), D. dimer protein (40.21%) as compared with normal values .Lipid profile observed significant increase in total cholesterol in (P > 0.05) after the infection in percentage (64.1%), Low-density lipoprotein (LDL) between the patients in percentage (63.04%), triglyceride were reported significant increase in percentage (59.7%), very Low density lipoprotein (vLDL) in percentage (68.4%) as compared with the patients that reported normal values. Conclusion: COVID-19 (SARS-CoV-2) spread quickly and the males and the older ages more likely infected May due a weak in immune response and decline in respiratory function s, blood grouping (A) more infected may be due to the biologic difference among these populations. The study reported hematological and biochemical abnormal changes in patients infected with COVID-19.
ISSN: 1994-697X

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