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الرئيسية > Measurement of C Reactive Prot...>الوصف

Measurement of C Reactive Protein Concentration in Myocardial Ischemia and Infarction

المصدر: مجلة بحوث جامعة تعز - سلسلة الآداب والعلوم الإنسانية والتطبيقية
الناشر: جامعة تعز
المؤلف الرئيسي: Yousef, Amani Ali Esmail (Author)
مؤلفين آخرين: Alhamadi, Abduh Mohammed (Co-Author) , Taleb, Fuad (Co-Author)
المجلد/العدد: ع40
محكمة: نعم
الدولة: اليمن
التاريخ الميلادي: 2024
الشهر: يونيو
الصفحات: 284 - 317
رقم MD: 1495461
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, AraBase, HumanIndex
مواضيع:
أمراض القلب | الشريان التاجي | الأوعية الدموية | عضلة القلب
كلمات المؤلف المفتاحية:
Coronary Artery Disease (CAD) | Risk Factors | Ischemic Heart Disease | High Sensitive CRP | Myocardial Ischemia | Biomarker Are the Key Focal Points of the Study
رابط المحتوى:

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المستخلص: Background: Myocardial ischemia and infarction represent significant health concerns. Inflammation plays a crucial role in the pathophysiology of these conditions. The elevation of CRP levels, an acute-phase protein, signifies the inflammatory status and has been associated with the severity and prognosis of myocardial damage. Measuring C-reactive protein (CRP) concentration in myocardial ischemia and infarction has garnered significant attention due to its potential role as a biomarker for cardiovascular risk stratification. Patients and Methods: Subjects for the measurement of CRP concentration in myocardial ischemia and infarction include patients who present with symptoms of acute chest pain, such as angina pectoris or myocardial infarction. Blood samples are typically drawn on admission to the hospital and at various time intervals throughout hospitalization to measure CRP concentration. CRP concentration is one of several markers that are used to diagnose acute myocardial infarction, along with troponin levels, electrocardiography, and clinical symptoms Patients presenting with chest pain, suggestive of acute myocardial infarction or unstable angina. The study aimed to evaluate the diagnostic value of high-sensitivity crp (hs-crp) testing in this population, as well as the prognostic value of crp concentration in predicting adverse cardiovascular events. The study included 200 patients with chest pain and high sensitive crp concentration Result: This cross-sectional study included 200 patients who suggestive of acute myocardial infarction or unstable angina. 53% of included patients was diagnosed with myocardial ischemia and infraction and 47% was diagnosed with angina. The median age of included patients was 55 years old. The patients with MI were older than patients with angina (p=0.005). 64% of included patients were male. There was statistically significant difference between both groups regarding age, sex and job occupations. There is marked elevation in crp level in old patient. the present study observed elevated levels of CKMB in patients experiencing acute MI compared to those with chronic or subacute MI Conclusion: In conclusion, this study provided compelling evidence supporting the utility of C-reactive protein (CRP) as a biomarker for myocardial ischemia and infarction. The findings demonstrate a significant elevation in CRP levels among patients with myocardial infarction compared to those with angina. This aligned with previous research underscoring the role of CRP as an indicator of inflammation intricately linked with atherosclerotic disease progression and adverse cardiovascular outcomes. this study underscored CRP's utility as a predictor and prognosticator of myocardial infarction, independently or in conjunction with other biomarkers. It substantiated the role of inflammatory processes in MI pathogenesis and the need to incorporate CRP evaluation in the diagnosis and risk stratification of patients with suspected acute coronary events

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