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The Hepatoprotective Effect Of Carrot ( Daucus Carotal. ) As Antioxidant On Intoxicated Rats With CCL4

المصدر: مجلة بحوث التربية النوعية
الناشر: جامعة المنصورة - كلية التربية النوعية
المؤلف الرئيسي: Attia, A. M. (Author)
مؤلفين آخرين: Rehan, S. R. (Co-Author), Lotfia, B. H. (Co-Author), Shalaby, M. A. (Co-Author)
المجلد/العدد: ع9
محكمة: نعم
الدولة: مصر
التاريخ الميلادي: 2007
الصفحات: 170 - 190
ISSN: 2314-8683
رقم MD: 655323
نوع المحتوى: بحوث ومقالات
قواعد المعلومات: EduSearch
مواضيع:
مضادات الأكسدة | نبات الجزر | الفئران
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المستخلص: The effect of feeding dry powder of carrot at three graded concentrations (5,10,20 %) mixed with the basal diet to carbon tetrachloride (Ccl4) intoxicated male rats for 4 weeks was studied. Intoxication of rats was done by s/c injection of Ccl4 (1 ml/kg) in the first (treatment group) and the last (prophylaxis ) two days of feeding period, as a single dose per day. Results of this study revealed that prophylaxis is more powerful than treatment groups. Both groups significantly increased feed intake, body weight gain percent and feed efficiency ratio. Biochemical analyses cleared that carrot supplementation to diet significantly lowered serum total cholesterol, triglycerides and LDL cholesterol, but increased HDL cholesterol. Serum liver enzymes( AST and ALT) as well as concentrations of urea nitrogen, uric acid and creatinine decreased in rats fed carrot supplemented diet .Histopathological examinations of liver and kidneys of these rats showed a decrease or amelioration of pathological lesions and damages caused by Ccl4 intoxicated rats.
ISSN: 2314-8683

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