المستخلص: |
In vitro antifungal screening of five organic extracts of three seaweeds belong to Chlorophyta (Enteromorpha intenstinalis), and Rhodophyta (Hypnea musciformis and Laurencia papillosa) against three species of Candida. The marine algae were chosen primarily because they were readily available in the quantities necessary for extraction purposes and renewable prosperity. The tested seaweeds exerted a variety of antimycotic activities which makes them interesting for programs screening more safe and low cost alternative natural antimicrobial products. Cyclohexane extracts were almost the most active exhibiting a broad spectrum inhibitory action irrespective to the experimented algal extract . On the contrary some algal extracts did not show recognizable inhibitory actions, and some others enhanced some fungal species. The experimented fungal species exhibited variable responses to the tested algal extracts depending upon the experimented fungal and algal species as well as the applied extract. Interestingly, some algal extracts exerted higher antifungal potential in comparable with the patented antifungal medicine (Nystatin and Clotrimazole). The present study confirms the potential use of seaweed extracts as a source of antimicrobial compound and may constitute a basis for promising future applied research that could investigate the use of seaweeds. Finally we conclude that the Libyan coast is a source of bioactive compounds with potential applications in controlling undesired microorganisms
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