Local Antibody Responses in the Respiratory Tract and Intestine of Chicks Vaccinated With Variant IBV Vaccine CR88
| المصدر: | مجلة جامعة الزيتونة |
|---|---|
| الناشر: | جامعة الزيتونة |
| المؤلف الرئيسي: | Elzlitni, R. (Author) |
| مؤلفين آخرين: | Jones, R. C. (Co-Author) , Almesilaty, L. A. (Co-Author) , Alzenad, A. F. (Co-Author) , Elhafi, G. E. (Co-Author) |
| المجلد/العدد: | ع13 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2015
|
| الشهر: | مارس |
| الصفحات: | 30 - 42 |
| DOI: |
10.35778/1742-000-013-026 |
| ISSN: |
2523-1006 |
| رقم MD: | 840633 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | EduSearch, HumanIndex, IslamicInfo, EcoLink |
| مواضيع: | |
| رابط المحتوى: |
عدد مرات التحميل
3
| المستخلص: |
The present study aimed to examine the immunogenicity of CR88 vaccine in terms of local isotypic and neutralising antibodies in the respiratory and enteric tracts in chicks vaccinated via spray or by a simulated drinking water route. In this respect, local virus-specific IgA, IgM and IgG were detected in serum, tears, and tracheal and intestinal washes from chicks vaccinated orally (simulating drinking water application) or by spray with variant IBV CR88 live vaccine, using specific monoclonal antibodies. All were detected in these secretions and oral application was consistently more successful than spray. Virus-neutralising activity was found in all secretions including pooled secretions from the intestinal regions, suggesting an effective immune response. |
|---|---|
| ISSN: |
2523-1006 |
عناصر مشابهة
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