المستخلص: |
The present study was performed to evaluate the effect of wheat germ and fermented wheat germ on some Immunoglobulin’s productions, lipids profile and liver functions in cirrhotic rats by Ccl4. Rats were divided into eight groups, control groups (1&2) negative and positive were fed on basal diet without supplementation. All treated cirrhotic groups. (3:8) were fed on experimental diets with raw or fermented wheat germ by different levels (5, 10 &15%). Results clearly revealed that fermented wheat germ recorded the highest values in Vitamin (A), (E) and (C), comparing with raw wheat germ. The best treatment were fermented wheat germ.(15%) and raw wheat germ (15%) which had lowest values of total lipid , triglycerides total cholesterol LDL, VLDL, AST, ALT and had the highest values of HDL respectively. While, all groups administrated fermented wheat germ by different levels (5, 10, 15%) had the highest values of serum level of interferon gamma (INF-y) and interleukin -10 (IL-10) respectively. It could be concluded that wheat germ and fermented wheat germ improve some Immunoglobulin’s production, lipids profile and liver functions especially fermented wheat germ 10 and 15% which has a best significant protective effect against acute hepatotoxicity induced by CC14 in rats.
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