المستخلص: |
Background: A new onset of ceftriaxone resistance is serious complication of therapy which is leading to a new treatment strategies or drugs. The aim of this study was to identify ceftriaxone regimens, estimate the cost of it per prescription and determine the prescriber adherence to ceftriaxone prescription protocol. Methods: A retrospective observational hospital-based study, conducted in emergency room at Military Hospital Omdurman in period from October 2017 to March 2018, on patients who took ceftriaxone. The data collected by using a pretested designed data collection sheet. The collected data were analyzed by SPSS version (23). Results: A total of 90 patients were included in the study. 93.30% of patients received ceftriaxone for other conditions rather than for meningitis, pneumonia and enteric fever. The majority of studied patients were in the age group more than 60 years (35.6%), (50%) were females. Almost all patients studied did not make culture and sensitivity test and prescribed by brand name. Most patients were dosed as 1g (83.30%), took BID (72%) and duration of therapy was found to be high in the range 5-7 days and 7-14 days (32.2%). Most of the interaction made by co-administration of other drugs with ceftriaxone was serious (50%). The cost was found to be high. Conclusions: The prescribing pattern of ceftriaxone according to it is regimens written by doctors, the cost and adherence of the prescriber to ceftriaxone prescription protocol reveal that irrational use of ceftriaxone or improper use.
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