المصدر: | المجلة العلمية لكلية التربية |
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الناشر: | جامعة مصراتة - كلية التربية |
المؤلف الرئيسي: | Elwahaishi, Salem (Author) |
مؤلفين آخرين: | Mohamed, Wesam F. A. (Co-Author) , Hargreaves, Alan (Co-Author) , Mills, Chris Lloyd (Co-Author) |
المجلد/العدد: | س5, ع12 |
محكمة: | نعم |
الدولة: |
ليبيا |
التاريخ الميلادي: |
2019
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الشهر: | مارس |
الصفحات: | 14 - 27 |
رقم MD: | 1007708 |
نوع المحتوى: | بحوث ومقالات |
اللغة: | الإنجليزية |
قواعد المعلومات: | EduSearch |
مواضيع: | |
رابط المحتوى: |
المستخلص: |
This study was designed to investigate the effect of the in vivo and in vitro exposure to the organo phosphorothioate pesticide diazinon, its metabolite diazinon oxon and diazinon in a commercial formulation on the AChE activity of the freshwater amphipod Gammarus pulex. Only diazinon oxon at concentrations of ≥ 50x103 nM oxon caused a significant inhibition of acetylcholinesterase (AChE) activity in vitro. However, diazinon oxon had no significant impact on the enzyme activity following in vivo exposure. The latter mode of exposure to either ≥ 10 nM of diazinon or ≥ 5 nM of the diazinon in the commercial formulation caused a significant reduction in AChE activity of treated organisms. This study supports the finding of previous studies that suggested AChE activity in aquatic animals as a valuable biomarker of diazinon. |
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