Synthesis, Characterization and Biological Activity of 2-Bis "1H Imidazole-2-Yl" Methylene Thiosemicarbazone and its Divalent Transition Metal Complexes
| المصدر: | المجلة العربية للتربية النوعية |
|---|---|
| الناشر: | المؤسسة العربية للتربية والعلوم والآداب |
| المؤلف الرئيسي: | Gobara, A. (Author) |
| مؤلفين آخرين: | Ahmed, Musa Hago Al Faki (Co-Author) |
| المجلد/العدد: | ع12 |
| محكمة: | نعم |
| الدولة: |
مصر |
| التاريخ الميلادي: |
2020
|
| الشهر: | أبريل |
| الصفحات: | 275 - 286 |
| DOI: |
10.33850/ejev.2020.73466 |
| ISSN: |
2537-0448 |
| رقم MD: | 1038290 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | EduSearch |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
Antimicrobial | Diffusion Method | Potato Dextrose Agar
|
| رابط المحتوى: |
عدد مرات التحميل
2
| المستخلص: |
2-bis (imidazole-2-yl ) methylene) thiosemicarbazone and its complexes with Pd (II), Cu (II), Hg (II), and Cd (II),ions have been prepared and characterized by elemental analysis, molar conductivity, spectroscopy (IR, uv. VIS, 1H NMR, mass spectrometry) and magnetic moment. The thiosemicarbazone coordinates to the metal ions via sulfur and azomethine nitrogen atom. The free ligand and its metal complexes have been tested in vitro against a number of microorganisms, to assess their antimicrobial properties. Antibacterial screening of the ligand and its complexes was conducted against Streptococcus pneumonia (G+), Bacillis subtilis (G+), Pseudomonas aeruginosa (G-), Escherichia coli (G-), also antifungal activity was examined against Aspergillus fumigates and Candida albicans. The experimental results show that nearly some complexes exhibit antibacterial activity highest than the free ligand but less than the standard. |
|---|---|
| ISSN: |
2537-0448 |
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