Protective Effects of Honey on Carbon Tetrachloride Induced Hepatotoxicity in Rats
| المصدر: | مجلة العلوم الإنسانية والتطبيقية |
|---|---|
| الناشر: | جامعة المرقب - كلية الآداب والعلوم قصر الأخيار |
| المؤلف الرئيسي: | Howas, Mahmoud Mohamed (Author) |
| مؤلفين آخرين: | Amer, Mohamed Ahmed (Co-Author) |
| المجلد/العدد: | ع10 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2020
|
| الشهر: | ديسمبر |
| الصفحات: | 255 - 262 |
| رقم MD: | 1104070 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | HumanIndex |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
Liver | Hepatotoxic | Free Radical | Antioxidation
|
| رابط المحتوى: |
عدد مرات التحميل
6
| المستخلص: |
The present paper aimed to evaluate the hepatotoxic effects of carbon tetrachloride and the hepatoprotective effects of bees' honey on rats, the experiment was carried out on four groups of female Wister rats. Hepatic lesions were induced by intraperitoneal (i.p) injection of carbon tetrachloride (0.5 ml/Kg body weight (b.wt)) diluted in olive oil (0.5 ml/Kg with 1:1 ratio), twice a week a period of for four weeks. Biochemical parameters of hepatic damage such as serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and catalase (CAT) activity were determined. Four weeks treatment using Carbon tetrachloride increased the serum AST, ALT and LDH levels significantly compared to control group (G1), while these enzymes were significantly reduced by the effect of honey (10%) plus CCl4 (0.5ml/Kg (b.wt) (i.p.)) for 4 weeks compared to CCl4 group (G3) (P<0.05), but there were significant decreases in catalase (CAT) values of CCl4 group (G3) compared to the control group (G1) (P<0.05). |
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عناصر مشابهة
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Hepatoprotective Potential of Propolis on Carbontetrachloride-Induced Hepatic Damages in Rats
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The Activity of some Herbs with or without Honey in Protecting the Liver against Carbon Tetrachloride Hepatotoxicity in Female Albino Rats
بواسطة: عمر، سارة محمود مصطفى منشور: (2022) -
Heart of Palm and its Expected Impact on Hepatotoxicity Induced by Carbon Tetrachloride in Rats
بواسطة: Abd El Zahir, Aziza H. منشور: (2022) -
Hepatoprotective Effects of Aqueous Purslane "Rejlah" Juice in Carbon Tetrachloride Induced Hepatotoxicity in Male Rats
بواسطة: الجزار، أمل فوزي محمود منشور: (2016) -
possible therapeutic and protective effects of nigella sativa oil on paracetamol-induced hepatotoxicity in male albino rats
بواسطة: Salama, Howaida Saber منشور: (2004)
