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Investigation of Chemical Constituents and Antimicrobial Activities of Salvia Officinalis L. Leaves Petroleum Ether Extract on Certain Pathogenic Microorganisms

المصدر: مجلة جامعة مروي التكنولوجية - عبد اللطيف الحمد
الناشر: جامعة عبد اللطيف الحمد التكنولوجية
المؤلف الرئيسي: Elsaim, Mawia Hassan (Author)
مؤلفين آخرين: Ali, Alaa (Co-Author) , Satti, Rajaa (Co-Author) , Elhussien, Mutasim H. (Co-Author)
المجلد/العدد: ع1
محكمة: نعم
الدولة: السودان
التاريخ الميلادي: 2018
الشهر: يناير
الصفحات: 71 - 84
ISSN: 1858-8522
رقم MD: 1260547
نوع المحتوى: بحوث ومقالات
اللغة: English
قواعد المعلومات: EduSearch, EcoLink, HumanIndex
مواضيع:
مضادات الميكروبات | التركيبات الكيميائية | النباتات الطبية
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المستخلص: The origin in Salvia officinalis (Lamiaceae) is a wild plant belong to Mediterranean region. Since it is important and famous use become farm by wide spread in all the world and in flowering sunny conditions. Salvia plant traditionally used, proved to be very effective for treatment of various infections and diseases and newly in modem medicine because it contains estrogen, phenolic acids, flavonoids, resin, saponins, silica, tannins, volatile oils. Preliminary Phytochcmical screening was carried out on Petroleum ether extract of Salvia leaves which revealed the presence of Sterols, Volatile oils, Triterpenes, Alkaloid, 2- deoxy sugar, Flavone aglycone, Anthraquinones and Carbohydrates as the main natural components. The antimicrobial effect of Salvia leaves has been investigated in order to test their activity against four Bacterial strains, Escherichia coli (E.C), Pseudomonas aeruginosa, (PS) (Gram -vc) and Bacillus subtilis (B.S), Staphylococcus aureus (S.A) (Gram + ve) and two fungal strains Candida Albicans (CA), Aspergillus Niger (AS) in (50, 25, 12.5. 6.5) mg/ mL concentrations. Petroleum ether extract showed a strong and superior anti- bacterial activity against four species E.C, S.a, PS, B.S respectively. The results is revealed that E.C: (Gram -vc bacteria) has a high sensitivity. The chemical compositions of the petroleum extract were analyzed by gas chromatographic mass spectroscopic analysis (GC/MS), and 94 component were recorded. The major components were Eucahyptol (20.04%), Camphor (10.99%), Coumarinc, Beta.-Pinene, Thujone (0.62%), Borneol, 8-allyl-7-hydroxy-6-cth, Vitamine A aldehyde, Limonene-1,2- cpoxidc(fr.1), Ledol, Caryophyllene, 3- Cyclohexene-1-methanol,. alpha., Naphthalene, Bornyl acetate, Tridccane, Dodecane, D-Limonene, Undecane.
ISSN: 1858-8522

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