Coagulation Abnormalities (D.Dimer) Induced by Beta-Lactam Antibiotics among Sudanese’s Patients in Khartoum State-2019
| المصدر: | مجلة كلية دلتا العلوم والتكنولوجيا |
|---|---|
| الناشر: | كلية دلتا العلوم والتكنولوجيا |
| المؤلف الرئيسي: | Hamid, Tarig A. M. (Author) |
| مؤلفين آخرين: | Elshekh, Yusra M. (Co-Author), Almostafa, Saria M. (Co-Author), Nurain, Aymen Mudawe (Co-Author) |
| المجلد/العدد: | ع14 |
| محكمة: | نعم |
| الدولة: |
السودان |
| التاريخ الميلادي: |
2021
|
| التاريخ الهجري: | 1443 |
| الشهر: | سبتمبر |
| الصفحات: | 1 - 8 |
| ISSN: |
1858-7038 |
| رقم MD: | 1260626 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | EduSearch |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
Beta–Lactam Antibiotic | D.Dimer | Sudan
|
| رابط المحتوى: |
عدد مرات التحميل
2
| المستخلص: |
Back ground Cephalosporins, along with penicillin, belong to the betalactam group of bactericidal antibiotics. Based on the timeline of drug discovery and their antimicrobial properties, these antibiotic agents are grouped into different generations, first through fifth. In general, as we move from first to third, the microbicidal activity of cephalosporins decreases against gram-positive organisms but increase against gramnegative bacilli. Furthermore, the resistance against beta-lactamases increases from first to fifth generations. Cefuroxime / Ceftin is an antibiotic ending for the second generation of cephalosporins. Sforioroxime is used for their medical studies of infection after the spectacular surgeries. Objective: The aim of this study was to assess the presence of d.dimer coagulation or decomposition in the blood of Sudanese patients who are treated with cerfouxime / ceftin. Method: 100 samples of blood were collected 50, samples of patients using the antibiotic cefroxime ceftinas the case, 50 sample of health personnel as control. 2.5 ml of blood collected in a sodium citrate vessel and subsequently measured to deny or prove the presence of blood clotting. Results: The results showed that the mean of D.dimer was increased when compare case group (2108) with control group (304) with statistically significant (p.value=0.00)and when associated with the concentration of antibiotics and time taken and there was a significant rise. Conclusion: The present study showed that there were an insignificant difference in the clotting or decomposition of d.dimer in the blood of patients who treated with antibiotic cefoxime / ceftin when compared with the control and no relationship between blood clotting when associated with sex and age |
|---|---|
| ISSN: |
1858-7038 |
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