The Prevalence of Anti-HBC Antibody among HBS Ag-Negative Libyan Blood Donors and its Association with HBV DNA in the Serum
| المصدر: | مجلة العلوم الإنسانية والتطبيقية |
|---|---|
| الناشر: | الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم |
| المؤلف الرئيسي: | Albakosh, Abdalla Muftah (Author) |
| مؤلفين آخرين: | Alshwin, Farag Omar (Co-Author) , Arshah, Tarek Mohamed (Co-Author) |
| المجلد/العدد: | ع30 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2017
|
| الشهر: | يونيو |
| الصفحات: | 76 - 82 |
| رقم MD: | 1260805 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | HumanIndex |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
HBV Infection | Anti-HBC | HBV-DNA | Blood Donors | Libya
|
| رابط المحتوى: |
| المستخلص: |
A hundred blood donors with hepatitis B surface antigen (HBs Ag) negative serology were enrolled in our study. These blood donors were investigated for the presence of antibodies to HBV core antigen (anti-HBc). Positive anti-HBc samples were further screened for anti-HBs antibodies, and for hepatitis B virus (HBV) DNA by real time Polymerase Chain Reaction technique. Results: The donors found to be Anti-HBc positive were 14 (represent 14% of all donors), among them 11 were positive for both Anti-HBcantibodies and anti-HBs antibodies, while three donors were positive for Anti-HBc antibodies alone. All Anti-HBc positive samples were investigated by Polymerase Chain Reaction technique and found to be negative for HBV-DNA (which it might be attributed to low sensitivity of the used Polymerase Chain Reaction technique). Despite that, it would be much safer to introduce anti-HBc screening for blood donors and discard all blood units which are positive for anti-HBc alone. |
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