Comparison between Fructose Amine and Hemoglobin A1C Level to Evaluate Glycemic Control in Sudanese Diabetic Control
| المصدر: | مجلة جامعة أم درمان الإسلامية |
|---|---|
| الناشر: | جامعة أم درمان الإسلامية - معهد البحوث والدراسات الإستراتيجية |
| المؤلف الرئيسي: | Elamin, Abdelsamee Elobied Mohamed (Author) |
| مؤلفين آخرين: | El-Neeima, Ahmed Mahdi Fadlallah (Co-Author) |
| المجلد/العدد: | ع35 |
| محكمة: | نعم |
| الدولة: |
السودان |
| التاريخ الميلادي: |
2022
|
| التاريخ الهجري: | 1443 |
| الصفحات: | 70 - 79 |
| ISSN: |
1858-5361 |
| رقم MD: | 1263609 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | IslamicInfo |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
Diabetes | Controlled | Fructosamine | HbA1c | Sudan
|
| رابط المحتوى: |
عدد مرات التحميل
3
| المستخلص: |
Background: Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases with high blood sugar levels over a prolonged period, and is one of the most severe and frequent human disorders. Fructosamine is a generic name given to a compound known as plasma protein ketoamines. Fructosamine together with glycated haemoglobin (HbA1c) are used to monitor the state of hyperglycaemia in diabetics. Objectives: This study aimed to compare between HeamoglobinA1c and Fructosamine in Sudanese diabetic patients in Omdurman Teaching Hospital and Diabetic and Endocrine center in Bahri. Materials and Methods: This is a cross-sectional study. Automated colorimetric determination of fructosamine for each of the 50 blood samples of the study group was carried out according to specific procedure. Latex enhanced immuno-assay method for hemoglobinA1c (HbA1c) determination based on the interaction between antigen molecules (HbA1c) and HbA1c specific c antibodies coated on latex beads was carried out according to a specific procedure. Control group criteria should be clear because it is confused. Results: HbA1c% and Fructose amine were measured on the same sample in 50 diabetic patients. There is a significantly direct positive correlation between levels of fructose amine (mmol/L) and HbA1c% among the studied group (P-value= 0.001<0.05). Sensitivity and specificity of fructosamine and HbA1c to detect blood glucose. hemoglobin A1C has (86%) sensitivity and (25%) specificity while fructosamine has (63%) sensitivity and (55%) specificity. Conclusion: In diabetes serum fructosamine assay can better reflect average blood glucose concentration over the previous 2-3 weeks and HbA1c is better reflective over the previous 8-10 weeks there for fructosamine can be used as routine test while HbA1C as a first -line screening test. |
|---|---|
| ISSN: |
1858-5361 |
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