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The Effect of Hemoglobin A1c on the Levels of Urea and Creatinine among Diabetic Patients, in Marzouk Region - Southern Libya

المصدر: مجلة البحوث العلمية
الناشر: جامعة أفريقيا للعلوم الإنسانية والتطبيقية
المؤلف الرئيسي: Alalem, Annour M. (Author)
مؤلفين آخرين: Noha, Ali M. (Co-Author), Ajadi, Almahdi M (Co-Author)
المجلد/العدد: مج2, ع4
محكمة: نعم
الدولة: ليبيا
التاريخ الميلادي: 2017
الصفحات: 10 - 18
رقم MD: 909231
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: HumanIndex
مواضيع:
كلمات المؤلف المفتاحية:
Diabetic Complications | Glycosylated Haemoglobin | Kidney Failure
رابط المحتوى:
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المستخلص: This study was conducted on 150 (74 males, 76 females) patients with diabetes attending Marzouk General Hospital and clinic with ages that ranges between 14-90 years. Blood samples along with some pertinent patients’ data were collected and recorded in a questionnaire. The cumulative sugar, urea and creatinine were measured. The results of this study showed that the mean values of urea and creatinine in patients with normal levels of urea and creatinine were 31.8 ± 8.6, 0.8 ± 0. 2 mg/dl respectively, While subjects with high levels of urea or creatinine were 64.8 ± 13.1, 1.6± 0.4 mg/dl respectively, and patients with high level of both urea and creatinine were 80.5 ± 38.5, 1.97 ± 0.7 mg/dl respectively. The mean values of urea, creatinine and glycosylated haemoglobin for diabetic patients with normal levels of urea and creatinine were 29.88 ± 6.44, 0.7 ± 0.2 mg/dl, 7.2 ± 1.6% respectively. While the mean values of urea, creatinine and glycosylated haemoglobin in patients with diabetes with high levels of urea and creatinine were 52 ± 5.1, 1.6 ± 0.6 mg/dl, 8.7 ± 2.8 % respectively. Comparing the statistical results of this study, the T-test shows that there are significant differences between the mean values of urea and creatinine and glycosylated haemoglobin with the value of P ˂ 0.05. Furthermore it is found that most patients with uncontrolled levels of glucose in the blood with appropriate dose of treatment for a prolonged period, leads to reduced ability of the kidneys for blood filtration and progresses to kidney failure over the years.