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الرئيسية > Antimicrobial Activities of Me...>الوصف

Antimicrobial Activities of Methanol Extract of Peganum harmala Leaves and Seeds against Urinary Tract Infection Bacteria

المصدر: مجلة التربوي
الناشر: جامعة المرقب - كلية التربية بالخمس
المؤلف الرئيسي: A., Khaled Abdusalam B. (Author)
مؤلفين آخرين: Alshadhli, Eman Mohammed (Co-Author) , Betro, Tasnim Adel (Co-Author) , Kara, Amera Lutfi (Co-Author) , Almashloukh, Mawada Bezain (Co-Author)
المجلد/العدد: ع23
محكمة: نعم
الدولة: ليبيا
التاريخ الميلادي: 2023
الشهر: يوليو
الصفحات: 731 - 739
ISSN: 2011-421X
رقم MD: 1407667
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch
مواضيع:
المقاومة الميكروبية | بيغانوم هارمالا | المسالك البولية | الطب البديل
كلمات المؤلف المفتاحية:
Antimicrobial Activity | Peganum Harmala | Urinary Tract Infection
رابط المحتوى:
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المستخلص: The problem of microbial resistance continues to increase in all regions of the world, and even though a very large number of antibiotics have been produced in the last 30 years, microbial resistance is maintained because of the wide use of these drugs against many infectious diseases. Thus, natural products are seen as the alternative solution. Based on previous studies, Peganum harmala has been reported to exhibit several biological properties including antibacterial and antifungal. Thus, the main aim of this study is evaluating antibacterial activities of P. harmala against Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus, which isolated from infected patients in (Alassaba'a hospital, Alassaba'a, west of Tripoli). Agar disk diffusion technique was used for detecting the antibacterial activity, and the minimum inhibitory concentration was tested by serial dilution methods. The results showed that the growth of all tested bacteria were inhibited strongly by methanol extract of seeds at 1.0% with inhibition zones 14.66, 12.00 and 15.33mm against E. coli, k. pneumoniae and S. aureus respectively. Besides, MIC values ranged between 0.625 to 1.25 mg/mL. While, MBC values ranging between 1.25 to 5 mg/mL. On the other hand, methanol extract of leaves was also inhibit the growth of E. coli, k. pneumoniae and S. aureus with inhibition zones 11.00, 9.66 and 10.00mm respectively. As well as, MIC values ranging between 1.25 to 2.5 mg/mL, while MBCs value ranging between 2.5 to 5 mg/mL. In conclusion, methanol extract of P. harmala seeds exhibited strongly antimicrobial activity against E. coli, k. pneumoniae and S. aureus, thus it can be developed as anti bacterial agent.
ISSN: 2011-421X

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