The Antibacterial Activity of 5-Fluoro-Isatin Thiosemicarbazone Derivatives on some Pathogenic Bacteria
| المصدر: | مجلة التربوي |
|---|---|
| الناشر: | جامعة المرقب - كلية التربية بالخمس |
| المؤلف الرئيسي: | Soof, Sana Ali (Author) |
| مؤلفين آخرين: | Sauf, Mona A. (Co-Author) , Shakurfow, Fathi Abdallah (Co-Author) , Kahal, Fatma (Co-Author) |
| المجلد/العدد: | ع24 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2024
|
| الشهر: | يناير |
| الصفحات: | 892 - 898 |
| ISSN: |
2011-421X |
| رقم MD: | 1455275 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | EduSearch |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
5-Fluoro-Isatin Thiosemicarbazone | Antibacterial Activity | Gram Negative Bacteria
|
| رابط المحتوى: |
| LEADER | 02184nam a2200253 4500 | ||
|---|---|---|---|
| 001 | 2200618 | ||
| 041 | |a eng | ||
| 044 | |b ليبيا | ||
| 100 | |9 744906 |a Soof, Sana Ali |e Author | ||
| 245 | |a The Antibacterial Activity of 5-Fluoro-Isatin Thiosemicarbazone Derivatives on some Pathogenic Bacteria | ||
| 260 | |b جامعة المرقب - كلية التربية بالخمس |c 2024 |g يناير | ||
| 300 | |a 892 - 898 | ||
| 336 | |a بحوث ومقالات |b Article | ||
| 520 | |b Isatin based materials can exhibit a wide range of biological activities including antimicrobial, antiviral, antifungal, anthelmintic, antitumor, anti-HIV, anti-inflammatory, antidepressant, antioxidant, anticonvulsant, antitubercular, analgesic, and central nervous system depressant activities. In this study, six compounds containing 5-Fluoro-isatin thiosemicarbazone with fluorophenyl and nitrophenyl or fluorophenyl and nitrophenyl in different positions and zinc complexes were evaluated based on their biological activities. 5-Fluoro isatin -3-(N-2- Fluorophenyl) Thiosemicarbazone and 5-Fluoro isatin-3-(N-4-Nitro phenyl) Thiosemicarbazone were the strongest compounds affecting gram positive bacteria compared to the other compounds. Also, this compound indicated better antimicrobial activity than positive control antibiotics. Besides, 5-Fluoro isatin-3- (N-4- Fluorophenyl) Thiosemicarbazone showed large inhibition zone equal to 13 mm against to some gram negative bacteria such as Klebsiella pneumonia and Serratia marrescens. | ||
| 653 | |a البكتيريا الضارة |a المناعة البشرية |a مضادات الميكروبات |a المشتقات الكيميائية | ||
| 692 | |b 5-Fluoro-Isatin Thiosemicarbazone |b Antibacterial Activity |b Gram Negative Bacteria | ||
| 700 | |9 744907 |a Sauf, Mona A. |e Co-Author | ||
| 700 | |9 744904 |a Shakurfow, Fathi Abdallah |e Co-Author | ||
| 700 | |9 771079 |a Kahal, Fatma |e Co-Author | ||
| 773 | |4 التربية والتعليم |6 Education & Educational Research |c 065 |l 024 |m ع24 |o 1568 |s مجلة التربوي |t Educational Journal |v 000 |x 2011-421X | ||
| 856 | |u 1568-000-024-065.pdf | ||
| 930 | |d y |p y |q n | ||
| 995 | |a EduSearch | ||
| 999 | |c 1455275 |d 1455275 | ||
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