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A Systematic Review of the Interplay between Covid-19 and Non-Communicable Diseases

المصدر: المجلة العربية للنشر العلمي
الناشر: مركز البحث وتطوير الموارد البشرية - رماح
المؤلف الرئيسي: Alshehri, Mohammed Abdullah Ali (Author)
مؤلفين آخرين: Alatifi, Waleed Khalid Abdulqader (Co-Author) , Alqahtani, Salem Mohammed Ibn Salem (Co-Author) , Alshahrani, Abdullah Mohammed Muflih (Co-Author) , Alshahrani, Othman Nasser Mohammed (Co-Author)
المجلد/العدد: ع72
محكمة: نعم
الدولة: الأردن
التاريخ الميلادي: 2024
الشهر: أكتوبر
الصفحات: 1 - 8
ISSN: 2663-5798
رقم MD: 1547431
نوع المحتوى: بحوث ومقالات
اللغة: الإنجليزية
قواعد المعلومات: EduSearch, HumanIndex
مواضيع:
الرعاية الصحية | الأمراض المعدية | معدل الوفيات | جائحة كورونا "كوفيد-19"
كلمات المؤلف المفتاحية:
Non-Communicable Diseases | COVID-19 | Clinical Outcomes
رابط المحتوى:
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المستخلص: Since the onset of 2020, the COVID-19 pandemic has had a profound global impact. With the rising cases and fatalities, particular attention has been directed to individuals with non-communicable diseases (NCDs), who are especially vulnerable to the virus. This literature review aims to consolidate existing evidence regarding the relationship between NCDs and COVID-19. Methods: A systematic review of literature related to COVID-19 and non-communicable diseases was conducted, covering the period from January 2020 to May 2020. The search was performed on PubMed, utilizing a range of search terms to refine the final selection of studies. Ultimately, 25 papers were included in this review. Results: The findings indicate that individuals with specific chronic conditions, including diabetes, hypertension, cardiovascular diseases, chronic respiratory diseases, and chronic kidney and liver disorders, are at a heightened risk of severe COVID-19 outcomes. Importantly, once infected, these patients are significantly more likely to experience severe disease progression or mortality compared to the general population. Two primary mechanisms are proposed to explain this association: first, increased expression of ACE2 (angiotensin-converting enzyme 2) receptors, which facilitates viral entry; and second, a hyperinflammatory response, commonly referred to as a "cytokine storm." Notably, the review found no evidence suggesting that medications for diabetes or hypertension worsen the COVID-19 condition in patients with chronic illnesses. Conclusions: The evidence supports a continued standard approach to disease management for patients with NCDs, albeit with enhanced monitoring. However, due to the ongoing vulnerabilities presented by COVID-19, prioritizing individuals with NCDs for vaccination should be a key focus for health authorities.
ISSN: 2663-5798

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