Synthesi and Reaction Mechanism of Some Compounds Realated to Thie No " 2,3-D " Pyrimidine Moiety
| المصدر: | مجلة العلوم الإنسانية والتطبيقية |
|---|---|
| الناشر: | الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم |
| المؤلف الرئيسي: | Mussa, Suliman M. (Author) |
| مؤلفين آخرين: | Al Bahi, Lamia A. (Co-Author) |
| المجلد/العدد: | ع28 |
| محكمة: | نعم |
| الدولة: |
ليبيا |
| التاريخ الميلادي: |
2016
|
| الشهر: | يونيو |
| الصفحات: | 1 - 20 |
| رقم MD: | 829400 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | الإنجليزية |
| قواعد المعلومات: | HumanIndex |
| مواضيع: | |
| كلمات المؤلف المفتاحية: |
Synthesis | Mechanism | Thienopyrimidine | Pyrimidothienopyrimidine | Biological
|
| رابط المحتوى: |
عدد مرات التحميل
4
| المستخلص: |
5-Amino-6-benzoyl-4-methyl-2-phenylthieno[2,3-d]pyrimidine (3) and 5-Amino-4-methyl- 2-phenylthieno[2,3-d]pyrimidin-6-carboxamide (5) , were prepared from 5-Cyano-4- methyl-2-phenylpyrimidin-6(lH)-thione(l). The reaction of compound 5 with some carbonyl compounds lead to the formation of pyrimidothienopyrimidinone derivatives 6 - 9.Compound 7was used as precursor for synthesis of4-Methyl-2-phenyl-6- (substitutedmethyl)pyrimido[4,5:4,5]thieno[2,3-d]pyrimidin-8(7H)-one ( 10 - 13) by reaction with different amines .Compounds 3, 5, 7 and 13 were selected and screened in vitro for their biological activity against breast carcinoma and lung carcinoma . |
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عناصر مشابهة
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Synyhesis and Reaction Mechanism of Some Compounds Re Lated To Furo[2,3-D][Pyrimidines And Pyrimido[4\\,5\\; 4,5 ]Furo[2,3 D][Pyrimidines
بواسطة: Mussa, Suliman M. منشور: (2016) -
Synthesis of Some New Pyrazolo [3,4-d] Pyrimidine Derivatives
بواسطة: Mussa, Suliman M. منشور: (2007) -
Synthesis of Some New Heterocyclic Compounds with Expected Biological Activity from a,B-Unsaturated Carbonyl Compounds
بواسطة: Abouzead, Hematsalama Khalaf Abd El Fattah منشور: (2009) -
Synthesis and Biological Activity of Some New 2-(2,4 dimethoxyphenylpyrrolo [2,3-d] Pyrimidine Compounds
بواسطة: Musa, Suliman M. منشور: (2014) -
Synthesis of Some Heterocyclic Compounds Containing Tetrahydroisoquinoline Moiety
بواسطة: Al-Iraqi, Mohammad Ahmad منشور: (2013)
